Books · Therapy101
On this page
  1. Book details
  2. What it is & historical context
  3. Core clinical themes & arguments
  4. Clinical practice, reception & legacy
  5. Reader level & educational scope
  6. Paired academic and clinical scholarship
  7. Source-mapped claims and evidence notes
  8. Related reading
  9. Sources and inspection notes
Zindel V. Segal, J. Mark G. Williams and John D. Teasdale · 2013 edition · First published 2002Treatment Manual & Clinical GuideLevel: IntermediateISBN 9781462507504

Books / Cognitive & behavioural

Mindfulness-Based Cognitive Therapy for Depression

Zindel V. Segal, J. Mark G. Williams and John D. Teasdale present mindfulness-based cognitive therapy (MBCT), an eight-week group programme developed to help prevent depressive relapse. This record describes the second edition.

Book details

Author of listed edition: Zindel V. Segal, J. Mark G. Williams and John D. Teasdale

Edition: 2nd edition (© 2013; hardcover released 2012; 1st ed. © 2002)

Publisher: Guilford Press

Edition year: 2013

First published: 2002

Original title: Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse

Language and origin: English (Canada / United Kingdom)

ISBN: 9781462507504

Form and genre: Treatment Manual & Clinical Guide

Level: Intermediate

Historical era: 1980–2009 · Evidence-Based, Trauma & Integrative Era

Covers: Differential activation hypothesis of depressive relapse; Doing (driven-discrepancy) mode vs. Being mode of mind; Decentering / metacognitive awareness; 8-week MBCT group curriculum and 3-Minute Breathing Space

APA 7th reference: Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2013). Mindfulness-based cognitive therapy for depression (2nd ed.). Guilford Press.

What it is & historical context

The authors developed mindfulness-based cognitive therapy as an eight-week group approach to reduce depressive relapse. It combines mindfulness practices with elements of cognitive therapy. The first edition carried the subtitle A New Approach to Preventing Relapse. The second edition is catalogued with a 2013 copyright date; the publisher lists the hardcover release in October 2012.

Core clinical themes & arguments

The manual describes the differential activation hypothesis: after depression, a low mood may reactivate patterns of negative thinking. MBCT aims to help participants notice thoughts and feelings as passing experiences. This is a theoretical account, not a prediction that low mood will lead to relapse.

Clinical practice, reception & legacy

The book presents an eight-week group programme. A 2016 individual participant data meta-analysis pooled nine randomised trials involving people with recurrent depression and found lower relapse risk for MBCT than for non-MBCT controls over 60 weeks. The results should be read in the context of the participants and comparators in those trials.

Reader level & educational scope

This intermediate entry offers educational orientation. The study abstract was consulted; the full book and trial reports were not reviewed. Decisions about treatment belong in discussion with a qualified clinician.

Paired academic and clinical scholarship

Paired work: Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse: An Individual Patient Data Meta-Analysis From Randomized Trials (Willem Kuyken, Fiona C. Warren, Rod S. Taylor, Ben Whalley, Catherine Crane and colleagues, 2016)

Reference: Kuyken, W., Warren, F. C., Taylor, R. S., Whalley, B., Crane, C., Bondolfi, G., Hayes, R., Huijbers, M., Ma, H., Schweizer, S., Segal, Z., Speckens, A., Teasdale, J. D., Van Heeringen, K., Williams, M., Byford, S., Byng, R., & Dalgleish, T. (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: An individual patient data meta-analysis from randomized trials. JAMA Psychiatry, 73(6), 565–574.

An individual participant data meta-analysis pooled nine randomised trials (1,258 participants) and found lower relapse risk for MBCT than for non-MBCT controls over 60 weeks. The findings concern people with recurrent depression and the comparators studied.

Source-mapped claims and evidence notes

Claim 1: According to the differential activation hypothesis, vulnerability to depressive relapse is driven by the reactivation of ruminative cognitive-affective networks during ordinary, transient dips in mood. (This is a proposed account of vulnerability, not an explanation established for every person with depression. The full book was not reviewed for this entry.) [Source 1: Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2013). Mindfulness-based cognitive therapy for depression (2nd ed.). Guilford Press. (Original work published 2002)]

Claim 2: A 2016 individual participant data meta-analysis found lower depressive relapse risk with MBCT than with non-MBCT controls over 60 weeks among participants with recurrent depression. (The analysis pooled nine trials; findings are limited to the populations and comparisons studied and do not determine an individual treatment choice.) [Source 3: Kuyken, W., Warren, F. C., Taylor, R. S., Whalley, B., Crane, C., Bondolfi, G., Hayes, R., Huijbers, M., Ma, H., Schweizer, S., Segal, Z., Speckens, A., Teasdale, J. D., Van Heeringen, K., Williams, M., Byford, S., Byng, R., & Dalgleish, T. (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: An individual patient data meta-analysis from randomized trials. JAMA Psychiatry, 73(6), 565–574.]

Sources and inspection notes

  1. Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2013). Mindfulness-based cognitive therapy for depression (2nd ed.). Guilford Press. (Original work published 2002)

    Primary source · Checked 4 November 2026

    Supports: Publisher lists the second edition, its formats, hardcover release date and ISBN; the full book was not reviewed.

  2. Teasdale, J. D., Segal, Z. V., Williams, J. M. G., Ridgeway, V. A., Soulsby, J. M., & Lau, M. A. (2000). Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology, 68(4), 615–623.

    Peer-reviewed · Checked not yet checked

    Supports: Pending verification: Initial landmark multi-site RCT of MBCT for relapse prevention in recurrent depression.

  3. Kuyken, W., Warren, F. C., Taylor, R. S., Whalley, B., Crane, C., Bondolfi, G., Hayes, R., Huijbers, M., Ma, H., Schweizer, S., Segal, Z., Speckens, A., Teasdale, J. D., Van Heeringen, K., Williams, M., Byford, S., Byng, R., & Dalgleish, T. (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: An individual patient data meta-analysis from randomized trials. JAMA Psychiatry, 73(6), 565–574.

    Peer-reviewed · Checked 4 November 2026

    Supports: Abstract of the 2016 individual patient data meta-analysis of relapse prevention.

  4. Wellcome Collection. Mindfulness-based cognitive therapy for depression: A new approach to preventing relapse. Catalogue record.

    Book · Checked 4 November 2026

    Supports: Catalogue records the first edition title, authors and 2002 publication.

  5. WorldCat. Mindfulness-based cognitive therapy for depression, 2nd edition. Catalogue record.

    Book · Checked 4 November 2026

    Supports: Catalogue records the second edition with a 2013 copyright date.

An educational reference. It does not diagnose, recommend treatment, match people with therapists or offer crisis support.